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. 2019 Dec 9;8(12):2172. doi: 10.3390/jcm8122172

Table 5.

Bivariate and multivariate logistic regression analysis: odds of malignancy.

Bivariate Multivariate
Independent Variables OR 95% CI p OR 95% CI p
Age (years) 0.987 0.972–1.001 0.073 0.991 0.971–1.011 0.359
Sex (%) 0.637 0.149
 Male 1 (ref.) 1 (ref.)
 Female 0.872 0.494–1.539 0.578 0.275–1.216
Nodule size (mm) 0.938 0.920–0.957 <0.001 - - -
Nodule size (mm) <0.001 0.001
 ≥40 1 (ref.) 1 (ref)
 ≥20–<40 3.579 1.831–6.995 <0.001 3.329 1.284–8.630 0.013
 <20 9.26 4.526–18.944 <0.001 6.537 2.352–18.167 <0.001
Echogenicity (%) 0.015 - - -
 Hyperechoic 1 (ref.)
 Isoechoic 0.667 0.153–2.899 0.589
 Hypoechoic 2.169 0.582–8.087 0.249
Composition 0.001 0.020
 Mixed cystic and solid 1 (ref.) 1 (ref.)
 Solid 2.974 1.595–5.546 2.313 1.138–4.701
Margins (%) <0.001 0.003
 Regular 1 (ref.) 1 (ref.)
 Irregular 5.786 2.439–13.723 5.655 1.979–16.158
Microcalcifications (%) 0.001 - - -
 Absent 1 (ref.)
 Present 2.892 1.564–5.346

OR: odds ratio.