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. 2019 Dec 3;8(12):2127. doi: 10.3390/jcm8122127

Table 3.

Relative HRs (95% CI) compared to the group with UA level of 5–7 mg/dL for the association between mortality risks and uric acid levels among adults without diabetes and with diabetes.

Outcomes Non-DM
<5 (mg/dL)
N = 11,545
5–7 (mg/dL)
N = 11,895
7–9 (mg/dL)
N = 3030
≥9 (mg/dL)
N = 250
All-cause mortality (N = 1664)
un-weighted 1.02 (0.8–1.18) 1.0 (reference) 1.26 (1.06–1.49) * 2.44 (1.63–3.66) *
weighted a 1.03 (0.87–1.22) 1.0 (reference) 1.43 (1.15–1.79) * 2.41 (1.42–4.08) *
CVD mortality (N = 378)
un-weighted 1.06 (0.78–1.44) 1.0 (reference) 1.37 (0.96–1.95) 2.97 (1.37–6.45) *
weighted a 1.22 (0.82-1.82) 1.0 (reference) 1.76 (1.22–2.56) * 5.06 (1.69–15.15) *
Cancer death (N = 436)
un-weighted 1.06 (0.82-1.36) 1.0 (reference) 1.09 (0.79–1.49) 2.39 (1.17–4.90) *
weighted a 1.04 (0.75-1.45) 1.0 (reference) 1.25 (0.90–1.73) 1.43 (0.64–3.21)
CVD or Cancer death (N = 814)
un-weighted 1.06 (0.87-1.29) 1.0 (reference) 1.19 (0.94–1.51) 2.63 (1.56–4.45) *
weighted a 1.10 (0.84-1.43) 1.0 (reference) 1.42 (1.08–1.87) * 2.60 (1.21–5.58) *
DM
N = 973 N = 1141 N = 345 N = 47
All-cause mortality (N = 405)
un-weighted 1.33 (1.01–1.75) * 1.0 (reference) 1.69 (1.22–2.34) * 1.41 (0.65–3.08)
weighted a 1.66 (1.14–2.41) * 1.0 (reference) 2.17 (1.49–3.17) * 2.10 (0.87–5.06)
CVD mortality (N = 117)
un-weighted 0.71 (0.41–1.24) 1.0 (reference) 1.75 (0.95–3.23) 1.91 (0.45–8.11)
weighted a 0.91 (0.38–2.18) 1.0 (reference) 2.53 (1.18–5.41) * 0.89 (0.18–4.50)
Cancer death (N = 84)
un-weighted 1.82 (1.01–3.26) * 1.0 (reference) 1.81 (0.85–3.85) 2.60 (0.59–11.40)
weighted a 2.13 (0.84–5.42) 1.0 (reference) 2.13 (0.88–5.12) 4.51 (0.89-22.78)
CVD or Cancer death (N = 201)
un-weighted 1.10 (0.74–1.63) 1.0 (reference) 1.75 (1.09–2.81) 2.15 (0.77–6.04)
weighted a 1.36 (0.77–2.43) 1.0 (reference) 2.30 (1.34–3.96) * 2.60 (0.69–9.80)

a Data are weighted estimates. Adjusted for BMI, sex, age, race, HDL-Cholesterol, current smoking status, SBP and creatinine. * p < 0.05.