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. 2019 Dec 15;8(12):2217. doi: 10.3390/jcm8122217

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Vitreous samples collection during pars plana vitrectomy (PPV). Vitreous samples were collected from proliferative diabetic retinopathy (PDR) patients or non-PDR controls (CTRL). PDR patients underwent a primary PPV due to vitreous hemorrhage (VH) and were followed for a period of 2-years. A total of 18 patients were reoperated through a second PPV, due to recurrent vitreous hemorrhage (RVH) during the study’s protocol. Vitreous samples from these patients (post-RVH) were paired the primary PPV (pre-RVH). Vitreous from patients that were non-reoperated were categorized as non-RVH.