Figure 1.

Schematic diagram of genomic organization and chromatin state of the human PDSS2 gene locus. The genomic region of the PDSS2 gene (chr6:107, 441, 132-107, 901, 660, human species genomic assembly version, GRCh37/hg19) is schematically represented with the indicated tracks, including exon-intron structure, H6K27Ac markers, DNase I hypersensitive clusters, histone modifications, and vertebrates conservation. The chromatin state was indicated as active promoter (bright red), strong enhancer (orange), insulator (blue), transcriptional elongation (deep green), and weakly transcribed region (light green).