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. 2019 Dec 13;8(12):2201. doi: 10.3390/jcm8122201

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Mean changes in bioenergetics linked to the oxidative burst in blood cell subtypes from acute pancreatitis (P) patients and healthy volunteers (Hv). Changes in (A) oxygen consumption rates (OCR) and (B) extracellular acidification rates (ECAR) obtained in monocytes (M), lymphocytes (L) and neutrophils (L) in response to phorbol 12-myristate 13-acetate (PMA) to measure bioenergetics changes during the oxidative burst (A,B). Values are expressed as means ± SEM with biological repeats of N = 10 (Hv) and 15 (AP). Significant changes in blood cells from AP patients compared to healthy controls are denoted as ** p ≤ 0.01 and *** p ≤ 0.001.