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Hemodynamic recovery. Sacubitril/valsartan reduced E/A ratio, MR, TR velocity and Nt-ProBNP concentration. This hemodynamic effect ameliorates the NYHA class and reduce diuretic dose at follow-up. MR, mitral regurgitation from moderate to severe grade; E/A: peak e-wave velocity/ peak a-wave velocity ratio; TR velocity: tricuspid regurgitation peak velocity.
