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(a) Schematic representing a pH-responsive, reversible capping of the pore channels of a mesoporous silica nanoparticle (MSN) with poly(acrylic acid) (PAA) (blue polymer chains). The associated change in MR contrast is also shown. (b) A graph detailing the change in relaxivity with pH. (c) The reversible relaxivity switching with pH. Adapted from the work of [40] with permission from The Royal Society of Chemistry.
