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. 2019 Dec 12;8(12):2197. doi: 10.3390/jcm8122197

Table 2.

Concentration of individual ceramide molecular species in liver of obese females and males.

Ceramide
nmol/mg
Females Males
NGT IGT T2D NGT IGT T2D
C14:0-Cer 1.08 ± 0.23 0.89 ± 0.16 a 1.15 ± 0.12 * 0.81 ± 0.23 0.94 ± 0.19 0.92 ± 0.12
C16:0-Cer 17.81 ± 3.4 19.49 ± 2.5 22.99 ± 3.1 a,* 16.83 ± 3.50 19.25 ± 2.45 20.84 ± 3.71 a
C18:1-Cer 0.43 ± 0.09 0.40 ± 0.11 0.38 ± 0.08 0.33 ± 0.11 0.36 ± 0.10 0.35 ± 0.09
C18:0-Cer 1.21 ± 0.22 1.52 ± 0.17 a 1.80 ± 0.25 a,* 1.42 ± 0.48 1.68 ± 0.32 1.86 ± 0.36 a
C20:0-Cer 1.46 ± 0.30 1.62 ± 0.43 1.80 ± 0.28 a 1.48 ± 0.36 1.83 ± 0.33 a 1.79 ± 0.35
C22:0-Cer 15.11 ± 3.13 17.59 ± 2.47 20.48 ± 3.04 a 14.87 ± 3.54 18.49 ± 3.59 a 20.16 ± 2.67 a
C24:1-Cer 29.37 ± 6.01 31.20 ± 5.54 32.03 ± 6.49 29.48 ± 6.73 33.68 ± 5.64 35.85 ± 5.09 a
C24:0-Cer 22.40 ± 5.02 25.32 ± 4.55 27.74 ± 5.11 a 24.25 ± 5.39 27.16 ± 3.49 29.59 ± 3.37 a
Total Cer 88.87 ± 14.46 98.02 ± 12.22 108.37 ± 9.73 a 89.47 ± 17.17 103.41 ± 12.54 a 111.36 ± 11.15 a

Data expressed as mean ± standard deviation; NGT—normal glucose tolerance group; IGT—impaired glucose tolerance group; T2D—type 2 diabetes group; a p < 0.05 vs. NGT; * p < 0.05 vs. IGT.