Table 4.
Correlations between individual hepatic ceramide molecular species and selected anthropometric measurements in obese males.
| C14:0-Cer | C16:0-Cer | C18:1-Cer | C18:0-Cer | C20:0-Cer | C22:0-Cer | C24:1-Cer | C24:0-Cer | Total Cer | |
|---|---|---|---|---|---|---|---|---|---|
| OGTT at 0’ | r = 0.0574 | r = 0.3426 | r = -0.0391 | r = 0.1592 | r = 0.2715 | r = 0.4197 a | r = 0.2046 | r = 0.3566 | r = 0.3613 |
| p = 0.640 | p = 0.004 | p = 0.750 | p = 0.191 | p = 0.024 | p = 0.000 | p = 0.092 | p = 0.003 | p = 0.002 | |
| OGTT at 120’ | r = 0.0951 | r = 0.3978 a | r = 0.1038 | r = 0.2999 | r = 0.3384 | r = 0.4114 a | r = 0.2681 | r = 0.3486 | r = 0.3994 a |
| p = 0.437 | p = 0.000 | p = 0.396 | p = 0.012 | p = 0.004 | p = 0.000 | p = 0.026 | p = 0.003 | p = 0.000 | |
| HbA1c | r = 0.1008 | r = 0.356 | r = -0.0491 | r = 0.3009 | r = 0.3009 | r = 0.3953 a | r = 0.1997 | r = 0.3749 | r = 0.3666 |
| p = 0.410 | p = 0.003 | p = 0.689 | p = 0.012 | p = 0.012 | p = 0.000 | p = 0.100 | p = 0.002 | p = 0.002 | |
| BMI | r = 0.2188 | r = 0.3048 | r = 0.4503 a | r = 0.3253 | r = 0.3184 | r = 0.2292 | r = 0.2589 | r = 0.0318 | r = 0.2463 |
| p = 0.071 | p = 0.011 | p = 0.000 | p = 0.006 | p = 0.008 | p = 0.058 | p = 0.032 | p = 0.795 | p = 0.041 | |
| FAT% (DXA) | r = 0.2853 | r = 0.2735 | r = 0.5358 a | r = 0.247 | r = 0.2622 | r = 0.1707 | r = 0.2577 | r = 0.1113 | r = 0.2466 |
| p = 0.017 | p = 0.023 | p = 0.000 | p = 0.041 | p = 0.029 | p = 0.161 | p = 0.033 | p = 0.363 | p = 0.041 | |
| HOMA-IR | r = 0.062 | r = 0.2999 | r = 0.1268 | r = 0.1512 | r = 0.2754 | r = 0.1757 | r = 0.0719 | r = 0.1531 | r = 0.1797 |
| p = 0.669 | p = 0.034 | p = 0.380 | p = 0.295 | p = 0.053 | p = 0.222 | p = 0.620 | p = 0.289 | p = 0.212 |
Values show Pearson’s r correlation coefficient together with correlation p-value. Correlations in bold type are significant with p < 0.00095 (p-value of 0.05 after Bonferroni correction for multiple comparisons); OGTT—oral glucose tolerance test (0 min and 120 min); HbA1c—glycated hemoglobin; BMI—body mass index; FAT% (DXA)—percentage of body fat as measured by dual-energy X-ray absorptiometry; HOMA-IR—Homeostatic model assessment of insulin resistance; a p < 0.00095.