Table 3.
Univariate Analysis | ||||
---|---|---|---|---|
N | HR | 95%CI | p-value | |
GALNT14 | 0.632 | 0.321–1.245 | 0.185 | |
GG | 17 | |||
Non-GG | 68 | |||
Age | 1.022 | 0.611–1.709 | 0.934 | |
≤65 y | 46 | |||
>65 y | 39 | |||
Gender | 0.836 | 0.493–1.416 | 0.505 | |
Male | 56 | |||
Female | 29 | |||
CEA | 1.048 | 0.578–1.901 | 0.877 | |
≤5 ng/mL | 50 | |||
>5 ng/mL | 24 | |||
CA19-9 | 0.998 | 0.512–1.947 | 0.996 | |
≤37 IU/mL | 17 | |||
>37 IU/mL | 56 | |||
T-bilirubin | 1.08 | 0.622–1.875 | 0.784 | |
≤1.4 mg/dL | 26 | |||
>1.4 mg/dL | 50 | |||
Tumor location | 0.654 | 0.356–1.203 | 0.172 | |
Head | 67 | |||
Body & Tail | 17 | |||
Tumor size | 0.601 | 0.357–1.011 | 0.055 | |
≤10 cm3 | 41 | |||
>10 cm3 | 44 | |||
Free margin | 0.657 | 0.371–1.163 | 0.149 | |
Negative | 50 | |||
Positive | 23 | |||
Differentiation | 1.262 | 0.571–2.789 | 0.565 | |
Well & moderate | 71 | |||
Poor | 13 | |||
Tumor invasion | 0.914 | 0.282–2.959 | 0.881 | |
pT1–3 | 79 | |||
pT4 | 6 | |||
Regional LN | 0.644 | 0.383–1.085 | 0.099 | |
N0 | 39 | |||
N1-2 | 46 | |||
Metastasis | - | - | - | |
M0 | 85 | |||
M1 | 0 | |||
Peritoneal invasion | - | - | - | |
No | 85 | |||
Yes | 0 | |||
Vascular invasion | 0.959 | 0.518–1.776 | 0.895 | |
No | 66 | |||
Yes | 19 | |||
Lymphatic invasion | 0.648 | 0.378–1.108 | 0.113 | |
No | 34 | |||
Yes | 51 | |||
Perineural invasion | 0.93 | 0.517–1.673 | 0.81 | |
No | 22 | |||
Yes | 63 | |||
Adjuvant C/T | 1.323 | 0.789–2.219 | 0.289 | |
No | 55 | |||
Yes | 30 |
Abbreviations: PFS = progression-free survival, PDA = pancreatic ductal adenocarcinoma, GALNT14 = N-acetylgalactosaminyltransferase14, y = year, CEA = carcinoembryonic antigen, CA 19-9 = carbohydrate antigen 19-9, T-bilirubin = total bilirubin, LN = lymph node, C/T = chemotherapy, HR = hazard ratio, and CI = confidence interval.