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. 2019 Dec 16;8(12):2225. doi: 10.3390/jcm8122225

Table 3.

Cox hazard analysis of clinicopathological and genotypic parameters for PFS in PDA patients who underwent surgical resection (Group 2: n = 85).

Univariate Analysis
N HR 95%CI p-value
GALNT14 0.632 0.321–1.245 0.185
GG 17
Non-GG 68
Age 1.022 0.611–1.709 0.934
≤65 y 46
>65 y 39
Gender 0.836 0.493–1.416 0.505
Male 56
Female 29
CEA 1.048 0.578–1.901 0.877
≤5 ng/mL 50
>5 ng/mL 24
CA19-9 0.998 0.512–1.947 0.996
≤37 IU/mL 17
>37 IU/mL 56
T-bilirubin 1.08 0.622–1.875 0.784
≤1.4 mg/dL 26
>1.4 mg/dL 50
Tumor location 0.654 0.356–1.203 0.172
Head 67
Body & Tail 17
Tumor size 0.601 0.357–1.011 0.055
≤10 cm3 41
>10 cm3 44
Free margin 0.657 0.371–1.163 0.149
Negative 50
Positive 23
Differentiation 1.262 0.571–2.789 0.565
Well & moderate 71
Poor 13
Tumor invasion 0.914 0.282–2.959 0.881
pT1–3 79
pT4 6
Regional LN 0.644 0.383–1.085 0.099
N0 39
N1-2 46
Metastasis - - -
M0 85
M1 0
Peritoneal invasion - - -
No 85
Yes 0
Vascular invasion 0.959 0.518–1.776 0.895
No 66
Yes 19
Lymphatic invasion 0.648 0.378–1.108 0.113
No 34
Yes 51
Perineural invasion 0.93 0.517–1.673 0.81
No 22
Yes 63
Adjuvant C/T 1.323 0.789–2.219 0.289
No 55
Yes 30

Abbreviations: PFS = progression-free survival, PDA = pancreatic ductal adenocarcinoma, GALNT14 = N-acetylgalactosaminyltransferase14, y = year, CEA = carcinoembryonic antigen, CA 19-9 = carbohydrate antigen 19-9, T-bilirubin = total bilirubin, LN = lymph node, C/T = chemotherapy, HR = hazard ratio, and CI = confidence interval.