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IL1R2 was activated by IL1β. A) BMI1 protein expression was induced after different dose of IL1β treated for 6 h under serum‐free condition. B,C) icd‐IL1R2 expression was induced after IL1β treatment in a time‐ or dose‐dependent manner in SUM159‐IL1R2 cells. D) Neutralizing antibody pretreatment overnight inhibited IL1β‐induced BMI1 upregulation in SUM149 cells.
