Table 3.
Effects of bromocriptine‐QR vs placebo treatment for 24 wk on resting heart rate and blood pressure in subjects with baseline RHR ≥70
| Bromocriptine‐QR (B‐QR) (N = 243) | B‐QR within group change | Placebo (PL) N = 129 | PL within group change | B‐QR vs PL between‐group difference | |||
|---|---|---|---|---|---|---|---|
| Baseline | After 24 wk of treatment | Baseline | After 24 wk of treatment | ||||
| RHR (BPM) | 78.4 ± 0.5 | 73.6 ± 0.6 |
−4.8 P < .001 |
77.0 ± 0.6 | 75.6 ± 0.9 |
−1.5 P = .06 |
−3.4 P = .001 |
| Systolic BP (mm Hg) | 129.9 ± 0.9 | 127.1 ± 0.9 |
−2.8 P = .002 |
127.7 ± 1.1 | 128.5 ± 1.3 |
0.8 P = .6 |
−3.6 P = .02 |
| Diastolic BP (mm Hg) | 79.2 ± 0.6 | 76.8 ± 0.6 |
−2.4 P < .001 |
78.0 ± 0.7 | 77.5 ± 0.8 |
−0.5 P = .5 |
−1.9 P = .05 |
| MAP (mm Hg) | 96.1 ± 0.6 | 93.6 ± 0.6 |
−2.6 P < .001 |
94.6 ± 0.7 | 94.5 ± 0.8 |
−0.05 P = .9 |
−2.5 P =.02 |
Data shown as mean ± standard error of mean.
Abbreviations: BP, blood pressure; MAP, mean arterial pressure; RHR, resting heart rate.