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Outcomes of CLARITY[37]
| PRP (n=116) | Aflibercept (n=116) | P | |
|---|---|---|---|
| Mean VA (letters) | 79.3 | 82.6 | |
| Change VA (letters) | -2.9 | +1.3 | <0.001 |
| ≥10 letter improvement (%) | 2 | 5 | 0.45 |
| ≥10 letter loss (%) | 15 | 5 | 0.009 |
| ≥15 letter loss (%) | 6 | 5 | 0.72 |
| Need for PPV (%) | 6 | 1 | 0.066 |
| Development of center involved DME (%) |
8 | 3 |
PPV: Pars plana vitrectomy, VA: Visual acuity, DME: Diabetic macular edema, PRP: Panretinal photocoagulation
