Table 2.
Year 1/year 5 comparison of prevalence and intensity, by arm, in a cohort of 374 children (153 in CWT arm and 221 in SBT arm)
| Treatment arm§ | Prevalence* | Village-level intensity† | Individual-level intensity‡ | |||
|---|---|---|---|---|---|---|
| CWT arm | SBT arm | CWT arm | SBT arm | CWT arm | SBT arm | |
| Year 1; baseline (SD) | 65.4% (34.0) | 54.5% (28.1) | 139.0 epg (113.0) | 103.6 epg (158.5) | 177.9 epg (100.2) | 133.2 epg (152.3) |
| Year 3 (SD) | 31.2% (20.4) | 33.1% (20.2) | 16.1 epg (17.1) | 16.5 epg (22.8) | 39.5 epg (36.8) | 36.1 epg (30.7) |
| Year 5 (SD) | 35.3% (18.8) | 46.5% (39.1) | 17.5 epg (15.7) | 25.2 epg (29.0) | 44.9 epg (22.9) | 36.3 epg (30.3) |
| Absolute difference between year 5 and baseline | 30.1% | 8.0% | 121.5 epg | 78.4 epg | 133.0 epg | 96.9 epg |
| Relative difference between year 5 and baseline (% change) | 46.0 | 14.7 | 87.4 | 75.7 | 74.8 | 72.7 |
| ANOVA table‖ | ||||||
| Effect of arm (CWT vs. SBT) | F(df1) = 0.000, P = 0.99 | F(df1) = 0.049, P = 0.83 | F(df1) = 0.193, P = 0.68 | |||
| Effect of year (year 1 vs. year 5) | F(df1) = 4.436, P = 0.089 | F(df1) = 4.607, P = 0.085 | F(df1) = 7.467, P = 0.041 | |||
| Effect of interaction (arm × year) | F(df1) = 1.496, P = 0.28 | F(df1) = 0.215, P = 0.66 | F(df1) = 0.184, P = 0.69 | |||
Bold value indicates statistical significant difference.
* Means of the prevalence of individual village.
† Mean of the means of individual villages, all investigated children included.
‡ Mean of the means of individual villages, only infected children included.
§ CWT arm = four times community-wide treatment; SBT arm = twice school-based treatment alternating with years without treatment.
‖ Two-way mixed-model ANOVA.