Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Dec 17;21(2):867–875. doi: 10.3892/mmr.2019.10889

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © Geng et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

PMC Copyright notice

Figure 3. — Clinical association and prognostic value of SHOC2 expression for breast cancer. (A) Relative mRNA expression levels of SHOC2 in fresh clinical samples. (B) IHC staining scores for the normal breast and invasive breast cancer tissues. (C and D) IHC staining shows that SHOC2 expression was low in normal breast tissues; (C) magnification, ×50 and (D) magnification, ×200. (E and F) IHC staining shows that SHOC2 was upregulated in invasive breast cancer tissues; (E) magnification, ×50 and (F) magnification, ×200. (G) Kaplan-Meier plot showing a significant association between SHOC2 expression and OS for patients with breast cancer. (H) In the ER (+) subgroups, OS rates were not significantly affected by SHOC2 expression. (I) In the ER (−) subgroups, OS rates were significantly affected by SHOC2 expression. **P<0.01. ER, estrogen receptor; IHC, immunohistochemistry; OS, overall survival; SHOC2, SHOC2 leucine rich repeat scaffold protein.