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Transcripts of Notch signaling components in streptozocin-induced diabetic rats. Expression levels of Notch1, Notch2, Notch3, Jag1 and Hes1 in diabetic rats were reduced in the DAPT group. mRNA expression levels were normalized against GAPDH. n=3. *P<0.05 and **P<0.01 compared with the sham group. DAPT, N-[N-(3,5-difluorophenacetyl)-L-alanyl]-S-phenylglycine t-butyl ester; Jag1, Jagged1.
