Table I.

Serum level of BUN and SCr in streptozocin-induced diabetic rats.

Groups	BUN, mmol/l	SCr, µmol/l
Sham	6.88±0.43	27.86±2.53
Vehicle	36.50±3.19a	118.96±5.15a
DAPT	20.19±2.43a,b	52.29±5.14a,b
DAPT + Cisplatin	25.51±2.72a,c	77.34±6.40a,c

^aP<0.05 vs. sham group

^bP<0.01 vs. vehicle group

^cP<0.05 vs. DAPT group. BUN, blood urea nitrogen; SCr, serum creatinine; DAPT, N-[N-(3,5-difluorophenacetyl)-L-alanyl]-S-phenylglycine t-butyl ester.