Table 4.

Odds ratio of process and patient composite scores

	Control	Intervention	Odds ratio IG vs CG
Change process score at 6M, number of (%)
Worsening 6M	445/1314 (33.87%)	309/855 (36.14%)
No change 6M	320/1314 (24.35%)	206/855 (24.09%)
Improvement 6M	549/1314 (41.78%)	340/855 (39.77%)
Change process score at 12M, number of (%)
Worsening 12M	610/1477 (41.30%)	377/1003 (37.59%)
No change 12M	224/1477 (15.17%)	166/1003 (16.55%)
Improvement 12M	643/1477 (43.53%)	460/1003 (45.86%)
Probability improvement/no worsening process score 6M (95% CI)
Improvement 6M	0.45 (0.38; 0.52)	0.43 (0.35; 0.51)
No worsening 6M	0.64 (0.58; 0.71)	0.63 (0.55; 0.69)	0.92 (0.61; 1.39)
Probability improvement/no worsening process score 12M (95% CI)
Improvement 12M	0.41 (0.34; 0.48)	0.43 (0.36; 0.51)
No worsening 12M	0.61 (0.54; 0.67)	0.63 (0.55; 0.69)	1.09 (0.73; 1.63)
Change patient score at 6M, number of (%)
Worsening 6M	49/475 (10.32%)	24/196 (12.24%)
No change 6M	352/475 (74.11%)	147/196 (75.00%)
Improvement 6M	74/475 (15.58%)	25/196 (12.76%)
Change patient score at 12M, number of (%)
Worsening 12M	60/407 (14.74%)	30/176 (17.05%)
No change 12M	246/407 (60.44%)	112/176 (63.64%)
Improvement 12M	101/407 (24.82%)	34/176 (19.32%)
Probability improvement/no worsening patient score 6M (95% CI)
Improvement 6M	0.20 (0.16; 0.25)	0.18 (0.13; 0.24)
No worsening 6M	0.88 (0.85; 0.91)	0.87 (0.81; 0.91)	0.87 (0.59; 1.29)
Probability improvement/no worsening patient score 12M (95% CI)
Improvement 12M	0.24 (0.19; 0.29)	0.19 (0.13; 0.25)
No worsening 12M	0.90 (0.87; 0.93)	0.87 (0.82; 0.91)	0.74 (0.49; 1.12)