Fig. 3.

Spatial succession of ARGs and OTUs and core resistome of the Han River. a Number of ARGs (clustered at 99% identity) maintained, gained, and lost in the downstream member of a pair of neighboring sites compared to the upstream member. b Relative abundance of ARGs maintained, gained, and lost in the downstream member of a pair of neighboring sites. c Unweighted proportion of OTUs maintained, gained, and lost in the downstream member of a pair of neighboring sites. d Weighted proportion of OTUs maintained, gained, and lost in the downstream member of a pair of neighboring sites. e List of ARGs belonging to the core resistomes of the Han River, the downstream sites, and the upstream sites. The core resistome was defined as ARGs detected in 90% or more of samples. f Relative abundances of core ARGs in the river samples. ARG density was imported from data shown in Fig. 1b.