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. 2020 Jan 7;18:8. doi: 10.1186/s12955-020-1269-8

Table 2.

Relationships between sociodemographic and clinical characteristics and quality of life of patients and FCs

Characteristic Total FACT-Leu score (Patients) SF-36 PCS score (FCs) SF-36 MCS score (FCs)
Mean ± SD Statistic p Mean ± SD Statistic p Mean ± SD Statistic p
Sex −2.03 (t) 0.044 −0.004 (t) 0.997 −3.573 (t) 0.004
 Male 74.65 ± 16.41 64.67 ± 14.76 48.92 ± 13.86
 Female 79.39 ± 16.19 64.68 ± 16.09 55.62 ± 12.40
Age (years) 2.259 (F) 0.107 3.798 (F) 0.024 2.587 (F) 0.078
  < 45 75.38 ± 16.11 66.88 ± 15.49 54.16 ± 14.33
 45–59 81.39 ± 16.20 60.52 ± 14.83 49.59 ± 11.54
 60–74 76.33 ± 18.70 65.75 ± 13.36 50.72 ± 11.33
Marital status −0.793 (t) 0.429 3.758 (t) < 0.001 4.626 (t) < 0.001
 Married 77.38 ± 16.31 63.18 ± 15.42 50.93 ± 12.94
 Unmarried 75.31 ± 16.81 75.42 ± 10.80 63.86 ± 11.98
Educational level 0.132 (F) 0.876 9.299 (F) 0.000 1.578 (F) 0.209
 Primary school or below 75.75 ± 12.86 55.96 ± 14.81 51.25 ± 12.47
 Middle or high school 77.29 ± 18.21 64.85 ± 14.85 51.57 ± 13.16
 University or higher 76.37 ± 14.38 70.10 ± 14.78 55.38 ± 14.64
Religious belief 0.039 (t) 0.969 0.332 (t) 0.740 −0.463 (t) 0.644
 Yes 76.75 ± 16.12 64.32 ± 17.16 52.95 ± 13.48
 No 76.85 ± 16.79 65.05 ± 13.51 52.05 ± 13.55
Employment −3.234 (t) 0.001 2.722 (t) 0.007 0.893 (t) 0.373
 Employed 65.80 ± 16.66 68.97 ± 14.66 53.76 ± 14.70
 Unemployed 78.05 ± 15.99 64.64 ± 15.44 51.92 ± 12.89
Type of leukemia −0.948 (t) 0.344
 AML 77.68 ± 17.14
 ALL 75.39 ± 15.24
Treatment −2.030 (t) 0.044
 Chemotherapy 75.66 ± 15.62
 Non-chemotherapy 81.70 ± 19.03
Undergoing initial treatment 0.680 (t) 0.498
 Yes 77.66 ± 15.43
 No 76.06 ± 17.30
Relationship to patient 1.126 (F) 0.346 4.644 (F) 0.001 4.621 (F) 0.001
 Spouse 78.17 ± 13.88 63.33 ± 15.13 51.66 ± 13.04
 Parent 73.06 ± 18.39 60.61 ± 15.67 49.26 ± 13.61
 Child 79.02 ± 19.30 67.99 ± 14.37 53.87 ± 13.75
 Sibling 72.14 ± 20.68 74.29 ± 15.78 62.78 ± 8.25
 Other 76.57 ± 6.58 81.79 ± 2.27 68.23 ± 1.66
Understanding of the disease 0.726 (F) 0.458 1.640 (F) 0.197
 Incomplete 59.50 ± 16.29 42.49 ± 7.42
 Partial 63.73 ± 16.11 52.11 ± 14.77
 Complete 65.82 ± 14.80 53.39 ± 12.29

ALL acute lymphoblastic leukemia, AML acute myelogenous leukemia, SD standard deviation, PCS physical component summary, MCS mental component summary, FC family caregiver, FACT-Leu Functional Assessment of Cancer Therapy-Leukemia, SF-36 36-item Short-Form Health Survey