Table 1.
Characteristics of the Patients. *
| Characteristic | Chemoradiotherapy (N = 370) |
Chemotherapy Only (N = 366) |
|---|---|---|
| Mean age (range) — yr | 60.5 (31–88) | 60 (31–85) |
| Race — no. (%)† | ||
| White | 291 (78.6) | 279 (76.2) |
| Black | 37 (10.0) | 42 (11.5) |
| Asian, other, or not specified | 42 (11.4) | 45 (12.3) |
| GOG performance status score — no.(%)‡ | ||
| 0 | 278 (75.1) | 268 (73.2) |
| 1 | 88 (23.8) | 96 (26.2) |
| 2 | 4 (1.1) | 2 (0.5) |
| FIGO stage — no. (%)§ | ||
| I or II | 6 (1.6) | 10 (2.7) |
| IIIA | 70 (18.9) | 81 (22.1) |
| IIIB | 12 (3.2) | 13 (3.6) |
| IIIC1 | 189 (51.1) | 166 (45.4) |
| IIIC2 | 90 (24.3) | 93 (25.4) |
| IVA | 3 (0.8) | 3 (0.8) |
| Histology and grade — no. (%) | ||
| Endometrioid, grade 1 | 87 (23.5) | 79 (21.6) |
| Endometrioid, grade 2 | 103 (27.8) | 118 (32.2) |
| Endometrioid, grade 3 | 64 (17.3) | 61 (16.7) |
| Serous | 66 (17.8) | 65 (17.8) |
| Clear cell | 10 (2.7) | 12 (3.3) |
| Mixed epithelial or other | 40 (10.8) | 31 (8.5) |
| Gross residual disease — no. (%) | ||
| Absent | 360 (97.3) | 359 (98.1) |
| Present | 10 (2.7) | 7 (1.9) |
| Median BMI (range)¶ | 32.0 (11.2–65.3) | 32.9 (18–60.2) |
| BMI category — no. (%) | ||
| Normal or underweight | 72 (19.5) | 71 (19.4) |
| Overweight | 84 (22.7) | 81 (22.1) |
| Obesity class I, II, or III | 214 (57.8) | 214 (58.5) |
*
There were no significant differences in baseline characteristics between the treatment groups. Percentages may not total 100 because of rounding.
†
Race was reported by the patient.
‡
A Gynecologic Oncology Group (GOG) performance status score of 2 or lower was required for enrollment (scores range from 0 to 5, with higher scores reflecting greater disability).
§
Stages were assigned according to the International Federation of Gynecology and Obstetrics (FIGO) 2009 classification; stages range from I to IV, with higher stages indicating more advanced spread of cancer.
¶
Body-mass index (BMI) is the weight in kilograms divided by the square of the height in meters.