Table 1.
Description of details related to subclasses of glucose transporter 1 family arranged in order of their percentage identity [HMIT full form: H+/myoinositol cotransporter]
| GLUT (Gene name) | Chromosomal localisation | Tissue localisation | Substrate specificity |
|---|---|---|---|
| CLASS I | |||
| GLUT1 (SLC2A1) | 1p35-31.3 | Ubiquitous distribution in tissues and culture cells | Glucose/Galactose |
| GLUT4 (SLC2A4) | 17p13 | Muscle, fat, heart | Glucose, not Galactose |
| GLUT3 (SLC2A3) | 12p13.3 | Brain and nerve cells | Glucose/Galactose |
| GLUT14 (SLC2A14) | Testis | Glucose/Galactose | |
| GLUT2 (SLC2A2) | 3q26-1-q26.2 | Liver, islets, kidney, small intestine | Glucose/Galactose/Fructose |
| CLASS II | |||
| GLUT5 (SLC2A5) | 1p36.2 | Intestine, kidney, testis | Fructose (Glucose) |
| GLUT7 (SLC2A7) | 1p36.22 | Small intestine, colon, testis | Glucose/Fructose, not galactose |
| GLUT9 (SLC2A9) | 4p16-p15.3 | Liver, Kidney | Glucose/Fructose, not galactose |
| GLUT11 (SLC2A11) | 22q11.2 | Heart, muscle | Glucose/Fructose, not galactose |
| CLASS III | |||
| GLUT6 (SLC2A6) | 9q34 | Spleen, leucocytes, brain | Glucose |
| GLUT8 (SLC2A8) | 9q33.3 | Testis, blastocyst, brain, muscle, adipocytes | Glucose/(Fructose) |
| GLUT10 (SLC2A10) | 20q13.1 | Liver, pancreas | Glucose/Galactose, not fructose |
| GLUT12 (SLC2A12) | 6q23.2 | Heart, prostrate, mammary gland | Glucose, Galactose, Fructose |
| HMIT (SLC2A13) | 12q12 | Brain | Myoinositol |