Table 1. .
Demographics, comorbidities and chemotherapy doses in patients and healthy subjects
| Parameter | Patients | Age-matched HS | p-value |
|---|---|---|---|
| Demographics | |||
| Count (females) | 21 | 21 | -- |
| Age (years) | 55 ± 8.8 | 54.5 ± 6.6 | 0.9 |
| DBP (mmHg) | 73.8 ± 11.7 | 69.5 ± 7.8 | 0.2 |
| SBP (mmHg) | 124.7 ± 14.1 | 123.8 ± 10.7 | 0.9 |
| HR (bpm) | 73.5 ± 11 | 71.2 ± 8.3 | 0.5 |
| Body Mass (kg) | 72.5 ± 14.6 | 72.7 ± 12.9 | 1.0 |
| BMI (kg/m2) | 27.0 ± 4.5 | 27.2 ± 4.4 | 0.9 |
| BSA (m2) | 1.8 ± 0.2 | 1.8 ± 0.2 | 1.0 |
| Comorbidities | |||
| Hypertension | 5 | 0 | 0.02* |
| Hypercholesterolemia | 4 | 0 | 0.04* |
| Diabetes mellitus | 5 | 0 | 0.02* |
| Chemotherapy dose | |||
| Doxorubicin 240 mg/m2 | 14 | - | - |
| Trastuzumab 8 mg/kg loading + 6 mg/kg/cycle | 7 | - | - |
| Radiotherapy | 8 | - | - |
HS, healthy subjects; DBP, diastolic blood pressure; SBP, systolic blood pressure; HR, heart rate; BMI, body mass index; BSA, body surface area.
a
indicates significant differences between patients and healthy subjects.