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. Author manuscript; available in PMC: 2020 Jan 8.
Published in final edited form as: J Orthop Res. 2017 Dec 29;36(6):1717–1727. doi: 10.1002/jor.23815

Figure 2: Short- and long-term effect of dexamethasone on MSC-laden HA constructs.

Figure 2:

(A) Study design to test for the effect of dexamethasone (DEX) on MSC chondrogenesis, (B) Equilibrium modulus (EY; kPa), (C) GAG (%WW), (D) Collagen (%WW), (E) Alcian blue staining at 4 weeks (the CM+ or DEX- group; top) and 8 weeks (the C-C, C-D, D-C or D-D group; middle and bottom), (F) GAG in media (μg/mL), (G) Nitrite in media (μM/mL). (the C-C group: constructs cultured in CM+ for the first 4 weeks followed by 4 weeks in CM+; the C-D groups: constructs cultured in CM+ for the first 4 weeks followed by 4 weeks in DEX-; the D-C group: DEX- for the first 4 weeks followed by CM+ for 4 weeks; the D-D group: DEX- for the first 4 weeks followed by DEX- for 4). (n = 4/group; lighter bars = 4w, darker bars = 8w; solid fill = CM+; pattern fill = DEX-; scale bar = 100 μm; 20X magnification; *p<0.05).