Table 2.
Differences in Spearman correlation coefficients among serum and intrahepatic HBV markers with pathological grades and stages.
Variable | HBeAg-positive (n = 254) | HBeAg-negative (n = 237) | ||||||
---|---|---|---|---|---|---|---|---|
Pathological grade | Pathological stage | Pathological grade | Pathological stage | |||||
r s | P | r s | P | r s | P | r s | P | |
Serum anti-HBc | 0.312ab | <0.0001 | 0.268c | <0.0001 | 0.270d | <0.0001 | 0.147e | 0.0237 |
Serum HBsAg | −0.248 | 0.0001 | −0.272 | <0.0001 | 0.183 | 0.0046 | 0.127 | 0.0503 |
Serum HBV DNA | −0.073a | 0.2470 | −0.128 | 0.0410 | 0.493d | <0.0001 | 0.411e | <0.0001 |
Intrahepatic HBsAg | 0.017b | 0.7825 | 0.030c | 0.6380 | 0.212 | 0.0010 | 0.221 | 0.0006 |
Intrahepatic HBcAg | −0.270 | <0.0001 | −0.254 | <0.0001 | 0.220 | 0.0007 | 0.169 | 0.0093 |
a–ePairwise comparisons between different Spearman correlation coefficients, P < 0.05, by Fisher's Z test. a: Z = 2.797, P=0.0052; b: Z = 3.425, P=0.0006; c: Z = 2.741, P=0.0061; d: Z = 2.846, P=0.0044; e: Z = 3.123, P=0.0018.