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. 2019 Dec 25;2019:6545642. doi: 10.1155/2019/6545642

Table 2.

Differences in Spearman correlation coefficients among serum and intrahepatic HBV markers with pathological grades and stages.

Variable HBeAg-positive (n = 254) HBeAg-negative (n = 237)
Pathological grade Pathological stage Pathological grade Pathological stage
r s P r s P r s P r s P
Serum anti-HBc 0.312ab <0.0001 0.268c <0.0001 0.270d <0.0001 0.147e 0.0237
Serum HBsAg −0.248 0.0001 −0.272 <0.0001 0.183 0.0046 0.127 0.0503
Serum HBV DNA −0.073a 0.2470 −0.128 0.0410 0.493d <0.0001 0.411e <0.0001
Intrahepatic HBsAg 0.017b 0.7825 0.030c 0.6380 0.212 0.0010 0.221 0.0006
Intrahepatic HBcAg −0.270 <0.0001 −0.254 <0.0001 0.220 0.0007 0.169 0.0093

a–ePairwise comparisons between different Spearman correlation coefficients, P < 0.05, by Fisher's Z test. a: Z = 2.797, P=0.0052; b: Z = 3.425, P=0.0006; c: Z = 2.741, P=0.0061; d: Z = 2.846, P=0.0044; e: Z = 3.123, P=0.0018.