Table 2. Literature review results of uterus transplantation as method of treatment and restoration of the MRKH syndrome.

MRKH: Mayer-Rokitansky-Kuster-Hauser

Author and date	Title	Type of research	No of participants	Conclusion
Diaz-Garcia et al., 2012 [9]	Uterine transplantation research: laboratory protocols for clinical application.	Review study		Recent advances in the field of solid organ transplantation and experimental Uterine transplantation provide a favorable and safe background in a scenario in which a human clinical uterine transplantation trial can take place.
Ozkan et al., 2013 [10]	Preliminary results of the first human uterus transplantation from a multiorgan donor.	Case study	1	The longest-lived transplanted human uterus case with acquirement of menstrual cycles is studied and described.
Brännström et al., 2014 [11]	First clinical uterus transplantation trial: A six month report.	Prospective observational study	9	This study shows that a live-donor uterine transplantation procedure has a low risk despite extended surgery duration. The report of the first successful human uterine transplantation case, defined as a live birth from a transplanted human uterus, has yet to be published.
Brännström et al., 2015 [12]	Live birth after uterus transplantation.		1	This report is a proof-of-concept for uterus transplantation as a treatment for uterine factor infertility. Furthermore, the results show the feasibility of live uterus donation, even from a postmenopausal donor.
Johannesson et al., 2015 [13]	Uterus transplantation trial: 1-year outcome.	Prospective observational study	9	The results of the present study demonstrate long-term uterine viability and function after live-donor uterine transplantation. Asymptomatic rejection episodes can be detected by cervical tissue biopsies and resolved by temporary addition of glucocorticoid treatment.
Brännström et al., 2017 [14]	Uterus transplantation and beyond. Journal of materials science.	Review study	11	Classical uterine transplantation procedure, with transplantation from live or deceased donors, will only stay as the predominant infertility treatment for Absolute uterine factor infertility women for one or two decades, since creation of bioengineered uterus may enter the clinical arena in the future.
Castellón et al., 2017 [15]	The history behind successful uterine transplantation in humans.	Review study	25	Uterus transplantation has demonstrated its potential as a highly effective treatment for infertility due to congenital or acquired uterine absence, especially in patients with Mayer Rokitansky Kuster Hauser Syndrome.
Suganuma et al., 2017 [16]	Uterus transplantation: Toward clinical application in Japan.	Review study	24	In total, 42 women worldwide have received transplanted wombs and 11 babies have been born up as a result until May 2017. It cannot be denied that uterine transplantation is still under development as a reproductive medicine and organ transplant procedure.
Zaami et al., 2017 [17]	Ethical and medico-legal remarks on uterus transplantation: may it solve uterine factor infertility?	Review study		Uterus transplant cannot be regarded as a life-saving procedure, but rather a method to restore woman ability to procreate, when lost, thus improving her quality of life. Uterus transplant is a complex surgical procedure and presents significant health threats.
Chmel et al., 2018 [18]	The Interest of Women with Mayer-Rokitansky-Kuster-Hauser Syndrome and Laparoscopic Vecchietti Neovagina in Uterus transplantation.	Prospective observational study	50	Nearly two-thirds of the Mayer Rokitansky Kuster Hauser syndrome study group of women with surgically created neovaginas were interested in uterus transplantation and motivated to undergo this method of absolute uterine factor infertility treatment.