Table 7. Binary logistic regression analysis to determine the effect of NOS3 polymorphisms, age, sex and smoking on POAG risk.
Variables | B | SE | Wald | Odds ratio (95% confidence interval) | p-value |
---|---|---|---|---|---|
Age | 0.02 | 0.01 | 3.60 | 1.02 (0.99–1.039) | 0.058 |
Sex | -0.11 | 0.23 | 0.23 | 0.89 (0.56–1.41) | 0.630 |
Smoking | 0.31 | 0.39 | 0.66 | 1.37 (0.64–2.93) | 0.416 |
rs2070744 | - | - | 2.66 | - | 0.265 |
C/T | -0.30 | 0.23 | 1.63 | 0.74 (0.46–1.17) | 0.202 |
C/C | 0.25 | 0.40 | 0.40 | 1.28 (0.58–2.82) | 0.529 |
rs1799983 | - | - | 5.82 | - | 0.054 |
G/T | 0.58 | 0.24 | 5.82 | 1.79 (1.11–2.89) | 0.016 |
T/T | 0.21 | 0.56 | 0.14 | 1.23 (0.41–3.70) | 0.709 |
Constant | -1.19 | 0.66 | 3.26 | 0.30 | 0.071 |
Trend and significant p-value in bold