Women and men from the HyperPATH cohort were genotyped according to the rs30187 gene variant as homozygous for the major allele (Homo Major), or heterozygous (Het) or homozygous for the minor allele (Homo Minor), the risk allele. Systolic BP (A) and diastolic BP (B) diastolic BP of females and males. Data are presented as mean ± SEM. P values were determined from multiple linear regression model analyses adjusted for age, race, BMI, disease state (HTN vs. normal BP), and site (Boston, Salt Lake City, Paris, Rome) for systolic BP coefficient: 3.4, P = 0.035; and for diastolic BP coefficient: 2.0, P = 0.05.