Figure 8. RPF in women and men according to rs30187 genotype.

Women and men from the HyperPATH cohort were genotyped according to the rs30187 gene variant as homozygous for the major allele, or heterozygous or homozygous for the minor allele, the risk allele. PAH clearance was used to estimate RPF. Data are presented as mean ± SEM. P value was determined from multiple linear regression model analyses for RPF in men adjusted for age, race, BMI, disease state (HTN vs. normal BP), and site (Boston, Salt Lake City, Paris, Rome); coefficient: 27, P = 0.038.