Table 2. Cox regression analysis for primary and secondary outcomes.

* adjusted for study, time to antibiotic commencement, prior challenge status, vaccine status.

	Azithromycin	Ciprofloxacin	p
Primary outcome
Bacteraemia clearance	N = 43	N = 15
Crude model	Ref	9.0 (4.2–19.3)	<0.001
Multivariable adjusted*	Ref	18.9 (6.6–54.0)	<0.001
Fever Clearance (Fever ≥38)	N = 27	N = 19
Crude model	Ref	2.1 (1.1–4.0)	0.03
Multivariable adjusted*	Ref	1.3 (0.6–2.8)	0.51
Secondary outcome
Stool shedding clearance	N = 19	N = 8
Crude model	Ref	1.4 (0.6–3.2)	0.48
Multivariable adjusted*	Ref	1.3 (0.4–4.2)	0.68
Fever Clearance (Fever ≥37.5)	N = 33	N = 23
Crude model	Ref	3.0 (1.6–5.5)	0.001
Multivariable adjusted*	Ref	2.4 (1.2–5.0)	0.02
Any symptoms	N = 50	N = 27
Crude model	Ref	1.9 (1.2–3.2)	0.01
Multivariable adjusted*	Ref	1.9 (1.1–3.2)	0.03