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. Author manuscript; available in PMC: 2020 Dec 1.
Published in final edited form as: Biomaterials. 2019 Sep 17;225:119493. doi: 10.1016/j.biomaterials.2019.119493

Table 1.

Change in thickness of leaflets and individual layers with increase in transvalvular pressure [78].

Transvalvular pressure Total thickness (μm) Fibrosa thickness (μm) Spongiosa thickness (μm) Ventricularis thickness (μm) Fibrosa thickness/total thickness (%) Spongiosa thickness/total thickness (%) Ventricularis thickness/total thickness (%)
Low pressures (PV) 265.7 ± 11.6 115.6 ± 4.7 88.3 ± 4.1 55.8 ± 3.9 43.8 ± 2.3 33.4 ± 2.0 20.7 ± 1.3
High pressures (PV) 188.8 ± 8.5 80.8 ± 5.1 58.7 ± 3.2 49.3 ± 1.9 42.6 ± 2.7 31.0 ± 1.6 26.4 ± 2.1
Low pressures (AV) 388.7 ± 21.7 262.2 ± 18.0 81.6 ± 1.0 89.9 ± 6.9 68.6 ± 10.6 21.8 ± 2.3 23.3 ± 2.6
High pressures (AV) 228.8 ± 9.3 142.7 ± 6.9 35.8 ± 3.7 60.9 ± 6.9 63.1 ± 6.0 15.0 ± 2.5 26.0 ± 4.0