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. 2020 Jan 8;40(2):395–410. doi: 10.1523/JNEUROSCI.1496-19.2019

Table 1.

Passive and active membrane properties following S1 and S11a

Session 1 (S1)
 Session 11 (S11)
Unpaired
 Paired
 Unpaired
 Paired
GFP− GFP+ GFP− GFP+ GFP− GFP+ GFP− GFP+
Resting Vm (mV) −69.35 ± 0.96 −67.30 ± 1.18 −68.73 ± 0.69 −68.95 ± 0.76 −66.75 ± 0.71 −67.16 ± 0.52 −68.42 ± 0.82 −68.32 ± 0.74
Rheobase (pA) 77.33 ± 6.83 103.27 ± 18.58 121.00 ± 16.69 75.14 ± 8.24* 82.57 ± 14.37 79.20 ± 5.36 86.71 ± 8.46 91.37 ± 10.26
Ri (mΩ) 160.38 ± 9.20 151.10 ± 14.11 138.48 ± 13.81 193.82 ± 15.19** 181.62 ± 21.67 143.14 ± 9.01 165.31 ± 13.39 161.89 ± 8.70
AP peak (mV) 67.00 ± 4.47 66.38 ± 3.26 68.71 ± 2.37 65.76 ± 3.53 68.40 ± 2.66 70.61 ± 2.22 67.19 ± 2.47 73.40 ± 2.23
AP half-width (ms) 1.30 ± 0.09 1.33 ± 0.07 1.21 ± 0.04 1.21 ± 0.05 1.28 ± 0.04 1.32 ± 0.04 1.33 ± 0.05 1.34 ± 0.04
Threshold (mV) −36.51 ± 0.85 −36.06 ± 1.47 −34.36 ± 1.00 −36.57 ± 0.94 −35.46 ± 0.74 −36.43 ± 0.77 −35.86 ± 0.65 −38.39 ± 0.54
fAHP (mV) −3.01 ± 0.40 −2.48 ± 0.35 −3.33 ± 0.42 −3.72 ± 0.47 −4.10 ± 0.52 −3.69 ± 0.48 −2.01 ± 0.30 −3.56 ± 0.42*
mAHP (mV) −11.12 ± 0.68 −9.93 ± 0.69 −11.91 ± 0.54 −10.51 ± 0.44 −11.54 ± 0.86 −10.37 ± 1.32 −9.39 ± 0.63 −11.47 ± 0.48

aElectrophysiological properties of GFP+ and GFP− pyramidal cells from Paired and Unpaired mice across conditioning sessions. Data are mean ± SEM. Liquid junction potential was −13.7 mV and was not adjusted for. Spike characteristics were determined from a single action potential (AP). When a doublet was elicited, the second spike was analyzed. Input resistance Ri was calculated from the slope of the I–V curve measured in response to 4 pA current steps ranging from −60 to 40 pA. Spike threshold was measured using the third differential with Mini Analysis software. The AP peak was calculated as the difference between the AP peak and AP threshold. Half-width was measured as the AP width at half-maximal spike. Postspike fast and medium afterhyperpolarizations (fAHPs and mAHPs) were measured ∼3 and ∼40 ms following the AP threshold, respectively. Sidak post hoc tests between GFP+ and GFP− are indicated.

*p < 0.05.

**p < 0.01.