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. 2019 Nov 13;8(1):347–356. doi: 10.1080/21623945.2019.1690834

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© 2019 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — Gene expression profile of peri-N in patients with CPA and EH.

(a) Heat map of genes related to lipid metabolism inflammation and fibrosis in peri-N between patients with EH and patients with CPA (fold change > 2.0 or fold change < −0.4; q value<0.05). EH, essential hypertension; CPA, cortisol-producing adenoma; peri-N, perirenal adipose tissue. (b) Pathway analysis showed the most typical pathways in CPA and EH samples. (c) Volcano plot showed differentially expressed genes in peri-N fat from patients with CPA compared with patients with EH. Green symbolizes markedly downregulated genes, and red symbolizes markedly upregulated genes. (fold change ≥2 and p value≤0.05). peri-N, perirenal adipose tissue.