Whole transcriptome analysis of MRPS31P5 silenced HFF cells and H-S silenced CJ-157 cells.
(A) left panel, Gene Ontology analysis of si-hMRPS31P5 downregulated genes in HFF; right panel, GO term analysis of upregulated genes. (B) Venn diagrams illustrating the overlap between common upregulated and downregulated genes in HFF with si-hMRPS31P5 and CJ-157 with si-H-S. There are 201 shared downregulated genes between HFF si-hMRPS31P5 and CJ-157 si-H-S, while 33 genes are commonly upregulated genes between HFF si-hMRPS31P5 and CJ-157 si-H-S. (C) GSEA of CJ-157 si-H-S against the top 200 downregulated or upregulated genes in MRPS31P5-silenced human HFF. (D) left, Gene Ontology analysis of CJ-157 si-H-S downregulated genes. right, Gene Ontology analysis of CJ-157 si-H-S upregulated genes.