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. 2019 Dec 26;11(24):11937–11954. doi: 10.18632/aging.102519

Figure 6.

Figure 6

Overexpression of hsa_circ_0006948 reverses the suppressive roles of miR-490-3p in ESCC. The migration (A) and invasion (B) abilities inhibited by miR-490-3p were reversed after co-transfection with hsa_circ_0006948 using transwell assay. (C) The expression of levels of vimentin, N-cadherin and HMGA2 were inhibited by down-regulated hsa_circ_0006948, but this effect was reversed by miR-490-3p inhibitor presented in Western blot analysis. (D) The expression of levels of vimentin, N-cadherin and HMGA2 were enhanced by up-regulated hsa_circ_0006948, but this effect was reversed by miR-490-3p mimics presented in Western blot analysis. * P<0.05, **P<0.01, ***P<0.001.