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. 2019 Dec 17;11(24):11988–12001. doi: 10.18632/aging.102524

Figure 7.

Figure 7

Mechanisms of circRNA AFF4 mediated fracture healing. CircRNA AFF4 acts as sponge of miR-7223-5p, leading to PI3K-AKT activation, which accelerates fracture healing via promoting cell proliferation and inhibiting apoptosis.