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. 2019 Dec 18;11(24):12032–12042. doi: 10.18632/aging.102534

Figure 2.

Figure 2

Compound 13 inhibited OGD-R-induced apoptosis activation in SH-SY5Y neuronal cells and primary neurons. SH-SY5Y human neuronal cells (A–D) or the primary murine hippocampal neurons (E and F) were pretreated (for 2h) with applied concentration (5/10 μM) of compound 13 (“C13”), followed by OGD-R stimulation for applied time periods, cell apoptosis was tested by the assays mentioned in the text. Bars stands for mean ± standard deviation (SD, n=5). * p<0.05 vs. “Mock” cells. # p<0.05 vs. cells with “OGD-R” treatment (no C13 pretreatment). Each experiment was repeated four times with similar results obtained.