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Percentage variance explained by PRS at analysed association levels for ASD. Percentage variance at eight association marker levels derived from linkage independent markers in the ASD genome-wide association study. Significance of associations between single nucleotide polymorphisms and ASD range from 0.5 to 1 × 10−6. Probability of association to be found at each individual variance level is denoted by P value.
ASD, autism spectrum disorder; PRS, polygenic risk score.
