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. Author manuscript; available in PMC: 2020 Jan 8.
Published in final edited form as: Biochem J. 2015 Feb 1;465(3):479–488. doi: 10.1042/BJ20140582

Figure 3. Time course of Cyp1a1 and Cre recombinase induction, and POR deletion in ERL mice following 3MC administration.

Figure 3

Adult male floxed POR mice without (−) or with CreCyp1a1 − KI (+ ; ERL) were given a single dose of corn oil or 3MC (40 mg/kg i.p.) and harvested 4, 9 or 14 days later. Whole cell lysates (Cre) or microsomes (POR, Cyp1a1 and GAPDH) were prepared and analysed by immunoblotting as described. At day 4, samples represent pools of duplicate samples; at days 9 and 14, individual samples are shown. Std = recombinant POR or Cyp1a1 standard.