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. 2020 Jan 1;16(2):320–329. doi: 10.7150/ijbs.37686

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E2F8 knockdown decreases tumor size in a xenograft nude mouse model. (A) ME180 cells transfected with shE2F8 or scrambled control were injected subcutaneously into the right dorsal scapula area of nude mice. Gross images of tumor masses from representative mice from each group. (B) Tumor sizes in the experimental groups. (C) Tumor weights were compared after tumor harvest. (D) Hematoxylin and eosin (H&E) staining of shE2F8-transfected ME180 cells (x200). (E) MRI image. *p<0.05 vs. scrambled control.