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. 2020 Jan 1;16(2):353–364. doi: 10.7150/ijbs.32331

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IL-15 contributes to the attenuation of Wnt signaling in CD8+ T cells. (A) TCF1 protein expression was detected in CD8+ T cell subsets by intracellular FACS staining after PBMCs were treated with cytokines indicated for 24 hr. Representative flow cytometry plots were shown from one of three independent experiments. (B-E) We observed a significant decrease in the portion of TCF1^high CD8 T cells in PBMCs from normal subjects that were treated with IL-15, but not with IL-6, IL-8, or SDF-1(stromal cell-derived factor-1, used as a non-SJS-related cytokine). * p< 0.05; two-sided Student's t-test.