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. 2019 Sep 2;39(2):368–384. doi: 10.1038/s41388-019-0993-1

Fig. 3.

Fig. 3

β3-AR regulates proliferation rate of human neuroblastoma BE(2)C cells through the involvement of SK2/S1P2 signaling. 3H-thymidine Proliferation Assay (1 μCi/well) of BE(2)C cell line treated with 1 μM SR59230A in presence or not of 10 μM CYM5520, 1 μM BRL37344 in presence or not of 1 μM ABC294640 and 1 μM JTE013, 1 μM Atenolol and 1 μM Propranolol for 24 h. Results are reported as mean ± SD of three independent experiments. Significance was calculated by one-way ANOVA analysis followed by Bonferroni’s post hoc test (**P < 0.01 SR vs. CTRL, ****P < 0.0001 BRL vs. CTRL; ####P < 0.0001 SR+CYM vs. SR; §P < 0.05 BRL+JTE vs. BRL; §§§§P < 0.0001 BRL+ABC vs. BRL)