Table 2.

Hematologic, renal, and cardiac response and progression rates.

	Old criteria (per protocol)	New criteria
Hematologic
N	92	92
Responders	48 (52%)	57 (62%)
CR	6	15
VGPR	12	22
PR	30	20
Renal
N	62	62
Responders	15 (24%)	31 (50%)
Time to response, median (range)	161 days (28–502)	62 days (28–480)
Progression	14 (23%)	27 (44%)
Time to progression, median (range)	196 days (21–1022)	144 days (26–1230)
Cardiac
N	71	71
Responders	11 (15%)	6 (8%)
Time to response, median (range)	213 days (58–995)	196 days (35–510)
Progression	10 (14%)	19 (25%)
Time to progression, median (range)	232 days (84–697)	30 days (23–396)