Table 1.

Baseline characteristics of the development and clinical validation datasets.

Characteristics	Development set	Primary clinical validation set	Secondary clinical validation set
Dataset	Thailand dataset	Thailand dataset	EyePACS-DME dataset
Number of patients	4035	697	554
Number of fundus images	6039	1033	990
Camera used for fundus images	Kowa VX-10	Kowa VX-10	Canon CR-DGi
OCT device used for determining ci-DME	Heidelberg Spectralis	Heidelberg Spectralis	Optovue iVue
Age: mean, years (SD)	55.6 (10.8) n = 6038	55.8 (10.8) n = 1033	62.0 (9.8) n = 990
Gender (% male)	60.8% n = 6036	62.4% n = 1031	50.1% n = 990
Central retinal thickness: mean, μm (SD)	263.8 (146.5) n = 6039	258.4 (132.8) n = 1033	254.4 (56.3) n = 990
ci-DME, Center Point Thickness ≥ 250 μm in Thailand dataset. Central Subfield Thickness ≥ 300 μm in the Eyepacs-DME dataset	28.3% n = 6039	27.2% n = 1033	7.8% n = 990
Subretinal fluid presence	15.7% n = 6039	15.1% n = 1033	NA
Intraretinal fluid presence	45.5% n = 6039	46.3% n = 1033	NA

It is noteworthy that the difference between total n and subcategories is missing data (e.g., not all images had age or sex)