Table 1.

Genetic screens in haploid cell systems

Aim of the screen	Cell type	Strain	Genes identified	Reference
Mismatch repair pathway	haESCs	Mouse	Msh2	Leeb and Wutz, 2011
Ricin toxicity	haESCs	Mouse	Gpr107	Elling et al., 2011
Olaparib resistance	haESCs	Mouse	Parp1	Pettitt et al., 2013
Promotion of exit from ground state	haESCs	Mouse	Zfp706, Pum1	Leeb et al., 2014
X inactivation	haESCs	Mouse	Spen	Monfort et al., 2015
Mn2+ induced toxicity	haNSCLCs*	Mouse	Park2	He et al., 2017
A803467 toxicity	haNPCs#	Rhesus monkey	B4GALT6	Wang et al., 2018
Block against spongiotrophoblast specification	haiTSCs	Mouse	Htra1	Peng et al., 2019

*haploid neural progenitor cells; ^#haploid neural stem-cell-like cells