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. 2019 Nov 28;69(1):33–42. doi: 10.1007/s00262-019-02434-5

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 1 — Representative immunohistochemical staining of V-domain Ig suppressor of T cell activation (VISTA) and PD-L1 in human ovarian cancer. a, b Negative PD-L1 and positive VISTA in immune cells (ICs) in high-grade serous ovarian carcinomas (HGSOC). c, d Negative PD-L1 and positive VISTA in tumor cells (TCs) and ICs in HGSOC. e, f Positive PD-L1 and positive VISTA in ICs in HGSOC. g, h Negative PD-L1 and positive VISTA in TCs in clear cell carcinoma. i, j Negative PD-L1 and positive VISTA in TCs in mucinous ovarian carcinoma. k, l Negative PD-L1 and positive VISTA in TCs, ICs, and endothelial cells (red arrows) in endometrioid carcinoma