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. Author manuscript; available in PMC: 2020 Jun 9.
Published in final edited form as: Nature. 2019 Dec 9;577(7789):244–248. doi: 10.1038/s41586-019-1786-y

Extended Data Figure 9: Phage ΦKZ escaper mutants are selected by Cas13-mediated RNA targeting.

Extended Data Figure 9:

Strain PAO1 expressing LseCas13a and a crRNA targeting the indicated gene. Plaque assays conducted as in Figure 1a using wild type and escaper mutant ΦKZ. WT ΦKZ is targeted by both strains and the faint clearings observed here are not observed as plaques in a full-plate assay. All plaque assays were replicated twice with similar results.