Figure 3. Biochemical representation of the Arabidopsis thaliana DME glycosylase domain. Blue, green and orange boxes represent three conserved domains of DNA glycosylases indicating domain A, glycosylase and domain B respectively, modified from [42]. Demeter (DME), Repressor of silencing1 (ROS1), Demeter-like2 (DML2), Demeter-like 3 (DML3), and Intrinsically disordered region (IDR).