Table 2.

Multiple regression results: relationship between neural responses to reward and aversion and depression severity and anhedonia symptoms^a

Brain region	Comment	X	Z	Y	z	P	β	f2
Anticipation phase	No significant correlations
Effort phase	Positive correlation between effort to avoid aversion (aversive hard–aversive easy) and anticipatory anhedonia (TEPS A)
Precuneus (BA7)		4	−56	46	3.67	0.01b	0.06	0.93
Insula		−36	−6	2	4.19	0.06c	0.06	0.91
Consummation phase	Negative correlation between aversive taste and consummatory anhedonia (TEPS C)
Caudate		−14	−4	26	4.39	0.006	−0.09	0.83

TEPS, Temporal Experience of Pleasure Scale; A, Anticipation; C, Consummation.

^a.For the effort conditions results remained the same when number of button presses were added as covariates of no interest. Beta values were extracted from SPM and f²-values were calculated by examining the brain data from plots in excel and running a correlation against the symptom questionnaires to get the r values.

^b.Becomes non-significant when age is removed as a covariate.

^c.Becomes more significant when age removed as a covariate.