Table 4.
Spoligotyping lineage conferring in gidB mutations among 302 clinical Mycobacterium tuberculosis isolates
| Codon | DNA/Protein changes | STRR | STRS | Spoligotyping lineages | Spoligotype description octonary | No. of isolates | Discovery |
|---|---|---|---|---|---|---|---|
| 7 | GCG-GCA/Silent | 1 | 0 | Beijing | 000000000003771 | 1 | Novel |
| 74 | TTG-TCG/Leu-Ser | 1 | 0 | Beijing | 000000000003731 | 1 | Novel |
| TTG-TTC/Leu-Phe | 1 | 0 | Beijing | 000000000003771 | 1 | Novel | |
| 77 | GTG-GCG/Val-Ala | 0 | 1 | Beijing | 000000000003771 | 1 | Novel |
| 85 | GAC-CAC/Asp-His | 0 | 1 | H3 | 777777777720771 | 1 | Novel |
| 91 | CTA-CGA/Leu-Arg | 1 | 0 | T3 | 577737777760771 | 1 | Novel |
| 166 | CGG-TGG/Arg-Trp | 0 | 1 | Beijing | 000000000003771 | 1 | Novel |
| 174 | CAC-CAG/His-Gln | 1 | 1 | Beijing | 000000000003771 | 2 | Novel |
| 194 | 582A insertion/Frameshift | 1 | 0 | T2 | 777777777760731 | 1 | Novel |
| 199 | 597C deletion/Frameshift | 0 | 1 | Beijing | 000000000003771 | 1 | Novel |
| 16 | CTT-CGT/Leu-Arg | 1 | 0 | LAM1 | 407777607760771 | 1 | Reported |
| 20 | CGG-GGG/Arg-Glu | 1 | 0 | Beijing | 000000000003771 | 1 | Reported |
| 34 | 102G deletion/frameshift | 1 | 0 | Beijing | 000000000003771 | 1 | Reported |
| 39 | 115C deletion/frameshift | 1 | 0 | T1 | 777777777760771 | 1 | Reported |
| 79 | TTG-TCG/Leu-Ser | 1 | 0 | T2 | 777777777760731 | 1 | Reported |
| 86 | CTC-TTC/Leu-Phe | 2 | 1 | Beijing | 000000000003771 | 3 | Reported |
| 117 | 351G deletion/Frameshift | 2 | 0 | Beijing | 000000000003771 | 2 | Reported |
| 118 | 352G insertion/Frameshift | 1 | 0 | Beijing | 000000000003771 | 1 | Reported |
| 352G insertion/Frameshift | 1 | 0 | New | 037777777740731 | 1 | Reported | |
| 163 | AAA-GAA/Lys-Glu | 1 | 0 | H3 | 777777677720771 | 1 | Reported |
| 178 | ATG-ATA/Met-Ile | 2 | 0 | Beijing | 000000000003771 | 2 | Reported |
| 92, 205 | GAA-GAC/Glu-Asp, GCA-GCG/Silent | 193 | 81 | Beijing | 000000000003771 | 274 | Reported |
| GAA-GAC/Glu-Asp, GCA-GCG/Silent | 2 | 1 | T1 | 777777777760771 | 3 | Reported | |
| GAA-GAC/Glu-Asp, GCA-GCG/Silent | 1 | 1 | T2 | 777777777760731 | 2 | Reported | |
| GAA-GAC/Glu-Asp, GCA-GCG/Silent | 1 | 0 | MANU2 | 777777777763771 | 1 | Reported |
Abbreviations: R, resistance; S, sensitive.